Facebook Desktop Application
There are many applications that lets you use Facebook on desktop, but not all give you a nice interface with almost all the Facebook features built in it.
Photo Uploader for Facebook is actually an Adobe AIR Facebook desktop application that lets you upload photos by simply drag-and-drop, but along with features to make a complete desktop app.
Simply click and drag an image (or folder of images) onto the running application. You can also stay constantly connected with your Facebook friends, view your News Feed, receive notifications, pokes and chat, right from your desktop without having to go into the browser.
Download Photo Uploader for Facebook
You can download this free Adobe AIR application from the Adobe marketplace from: Download Photo Uploader